
An electron micrograph of PCV2 virions.
Photo compliments of John Ellis, DVM, Ph.D., DACVP, DACVM, University of Saskatchewan, Saskatoon, Canada
- PCV2 is a member of the family Circoviridae, a recently established virus family that contains both PCV1 (does not cause disease in swine) and PCV21
- Circoviruses get their names from their DNA, which is a circular, single-stranded molecule1
- PCV2 is the smallest, freely replicating virus known in vertebrates2
- The circular PCV2 genome is only 1,767-1,768 nucleotides in length and only codes for two proteins – one determines viral replication and one establishes the viral coat 1,2
Genomic organization of PCV2.
Diagram compliments of Steven Krakowka, DVM, PhD, DACVP, The Ohio State University, Columbus, Ohio
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Reference
- Segalés J, Allan GM, Domingo M. Porcine circovirus diseases. Anim Health Res Rev 2005;6(2):119-42.
- Krakowka S. PCV2 & PCVADs. Suvaxyn Swine Update 2006;3. Fort Dodge Animal Health.
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