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PCVAD is diagnosed by a combination of clinical signs and laboratory confirmation.
According to Joaquim Segalés, DVM, PhD,1 the following criteria must be present or a diagnosis of PCVAD:
- Compatible clinical signs (wasting) and gross lesions
- Characteristic microscopic lesions in lymphoid tissues (lymphocyte depletion with granulomatous inflammation)
- Presence of PCV2 (antigen or nucleic acid) within lymphoid lesions
A herd case definition has been proposed by the EU consortium on PCVAD (project 513928):
- Clinical appearance of disease on the herd level with significant increase in postweaning mortality and wasting in pigs compared with historical levels in the herd
- Pathological and histopathological diagnosis of PCVAD with fulfillment of the criteria for individual cases of PCVAD
PCVAD can be confirmed only by demonstrating the presence of clinical signs, microscopic signs and actual virus in affected tissues.
For more information about diagnostics and sample selection, visit the Iowa State University Veterinary Diagnostic Laboratory website.
For more information about the EU consortium on control of PCVAD and its research, visit www.pcvd.org.
Reference
1. Segalés J. Clinico-pathological features in PMWS: PMWS herd and individual case
definitions. Proceedings, AASV Preconference Seminar #12: PCV2/PMWS:
Understanding Factors That Impact Disease Expression and Control; 2006 Mar 5;
Kansas City, MO. p. 1-7. |
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